Studydroid is shutting down on January 1st, 2019

by gringo


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Cox-1 and Cox-2 enzymes stimulate what?
Prostaglandins
Cox-1 enzymes are inhibited by what 7 meds?
ASA-Aspirin
Ibuprofen
Voltaren
Naproxen
Naproxen sodium (Aleve)
Daypro
Mobic
Cox-2 enzymes are inhibited by what med?
Celebrex
Cox-1 and Cox 2 inhibitors blcok the ezymes responsible for synthesis of prostaglandins which are responsible for producing what in the body?
inflammation
What med is a non-opioid analgesic and anitpyretic?
acetaminophen
Why does the body become inflamed?
Histamine response
What three things can cause a histamine response?
- injury
- response to a foreign body
- response to an allergen
Grandma is admitte do the emergency departmetn for weakenss, + pale, + tachypnea, + fatigue for over a week.  What nursing consideration should be taken?
blood count
What are supersupressors that decrease severe inlammation in all types of situations?
Corticosteroids
Corticosteroids can be used in what three conditions?
- asthma
- autoimmune disease
- arthritis
What are six serious adverse effects of Corticosteroids?
- adrenal insufficiency
- hyperglycemia
- mood changes
- peptic ulcers
- osteoporosis
- can mask the signs of infection
Corticocosteroids can make adrenal function stop causing what syndrome?
Cushing's Syndrome
What are three steps to take to avoid Cushings Syndrome?
- taper pt off o the med
- take med every other day
- short duration treatments
What is the goal of antipyretics?
Treat the cause of the fever while lowering the body temperature
Name three antipyretics.
Aspirin, Ibuprofen and acetaminophen
What is the antipyretic of choice for children?
acetaminophen
Giving aspirin to children younger than 18 has been associated with what syndrome?
Reyes Syndrome
Reyes syndrome is marked by what two conditions?
- increase ICP
- Increase lipids in the liver
What do you call a rapid release of chemical mediators of inflammation on a large scale throughout the body that is life threatening?
Anaphylaxis
Anaphylaxis is marked by H-1 receptors that give what five symptoms?
itching
pain
edema
vasodilation
bronchoconstriction
Anaphylaxis can occur as a result of any stimuli.  Name four common stimuli.
medication
foods
smells
stings
What are the 2 types of headaches?
- Tension

- Migraine
In tension headaches there are muscle contactions where?
head and neck
Name four symptoms of migraines.
- generally one-sided
- worsen with activity
- accompanied by visual or auditory complaints
- may be accompanied by nausea/vomiting and auras
What are 2 goas for treatment of migraines?
- stop a migraine
- prevent a migraine
What are the two major drug classes for migraine treatment?
Triptans
Ergo Alkaloids
Both classes of meds used to abort migraines are what type of agonists?
sertonin agonists
What are the two classes of drugs that prevent migraines?
- Inderal (beta blockers)
- Amitriptyline (antidepressant)
What do you call an overwhelming compulsion for drug use marked by physical and phychological dependence?
Addiction
What is dependence adapted to the nervous system?
Physical dependence
What is dependence where there is no obvious physical discomfort but more emotional and mental?
Psychological dependence
What occurs after physical dependence?  Can be severe with hallucinations, tremor and seizures.
Withdrawal
What can be a problem for those in chroic pain because normal process for medications is affecting the CNS?
Tolerance
What means becoming tolerant of like drugs?
Cross-tolerance
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